Anti-cd8 antibodies block priming of cytotoxic effectors and...

Details Anti-cd8 antibodies block priming of cytotoxic effectors and... Anti-cd8 antibodies block priming of cytotoxic effectors and...

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2728772

The present invention includes compositions and methods for inducing tolerance in a subject in need thereof comprising providing the subject with an effective amount of an anti-CD8 antibody sufficient in induce CD8+ T cell immune tolerance to allogeneic antigens.

La présente invention concerne des compositions et procédés pour induire une tolérance chez un sujet qui en a besoin, comprenant la fourniture au sujet dune quantité efficace dun anticorps anti-CD8 suffisante pour induire une tolérance immune aux cellules T CD8+ à des antigènes allogéniques.

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