Anti-cobra toxin antibody fragments and method of producing...

Details Anti-cobra toxin antibody fragments and method of producing... Anti-cobra toxin antibody fragments and method of producing...

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61P 39/02 (2006.01) C07K 16/18 (2006.01) C40B 40/06 (2006.01)

Patent

CA 2745473

A method of constructing a V HH library from an immunized camelid, using whole venom or an extract thereof There is also provided V HH antibody fragments isolated from a library produced in hyperimmunized llama These V HH antibody fragments were sequenced, and specifically bind .alpha.-cobratoxin.

Linvention concerne la constitution dune banque de VHH provenant dun camélidé immunisé, au moyen de venin total ou d'un extrait de venin. L'invention concerne aussi des fragments d'anticorps de VHH isolés d'une banque obtenue d'un lama hyperimmunisé. Ces fragments d'anticorps VHH sont séquencés et, se lient spécifiquement à la-cobratoxine.

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