C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2724409
The present invention provides antibodies that bind human CXCR4 and are characterized as having high affinity and strong neutralizing properties. The antibodies of the invention are useful in the treatment of tumorigenesis, including tumor growth, invasion, angiogenesis, or metastasis.
La présente invention concerne des anticorps de liaison au CXCR4 humain caractérisés en ce quils présentent une haute affinité et de fortes propriétés de neutralisation. Les anticorps selon linvention sont utiles dans le traitement de la genèse tumorale, comprenant la croissance, linvasion, langiogenèse, ou la métastase tumorales.
Dickerson Cindy Takeuchi
Marquis David Matthew
Obungu Victor
Peng Sheng-Bin
Vaillancourt Peter Edward
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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