Anti-diarrheic product and method of treating...

A - Human Necessities – 61 – K

Patent

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Details

A61K 38/17 (2006.01) A23L 1/305 (2006.01) A61K 35/20 (2006.01) A61K 35/55 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2148261

An anti-diarrheic product comprises a foodstuff and an anti-rotaviral agent such as human defatted fat globule membranes, the human milk macromolecular fraction, skim milk, curd, whey, the milk mucin complex, the 46 Kd app.MW glycoprotein, a polypeptide having an amino acid sequence having the rotavirus binding specificity of the 46 Kd app.MW HMFG glycoprotein or mixtures thereof. An anti-diarrheal kit comprises the anti-rotaviral agent of this invention and instructions for its use, and optionally a foodstuff. A method for inhibiting or countering rotavirus infection in mammalian cells comprises contacting the cells with an anti-rotaviral amount of the agent of this invention. A therapeutic method for inhibiting the onset of or countering rotavirus infection comprises administering to a subject afflicted with or at risk for rotavirus infections such as those occurring, for example, in infants and children (infantile gasteroenteritis) and immunodeficient persons or those who have received a transplant, an anti-rotaviral effective amount of the agent of this invention.

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