Anti-dnase-gamma antibody, and production and use thereof

Details Anti-dnase-gamma antibody, and production and use thereof Anti-dnase-gamma antibody, and production and use thereof

C - Chemistry, Metallurgy

07

K

C07K 16/40 (2006.01) C12N 5/12 (2006.01) C12P 21/00 (2006.01) G01N 33/573 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2321266

Polyclonal antibodies and monoclonal antibodies specific for DNase.gamma., hybridomas producing anti-DNase.gamma. monoclonal antibodies and an immunological detection method and purification method for DNase.gamma. using the antibodies are provided. By using a peptide containing the C-terminal portion sequence of the DNase.gamma. molecule as an immunogen it is possible to obtain anti-DNase.gamma. antibodies that specifically recognize DNase.gamma.. The DNase.gamma. monoclonal antibodies and polyclonal antibodies of the invention are characterized by specifically recognizing DNase.gamma. proteins.

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