Anti-fas recombinant antibodies and dna therefor

Details Anti-fas recombinant antibodies and dna therefor Anti-fas recombinant antibodies and dna therefor

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 16/28 (2006.01) C07K 16/46 (2006.01) C12P 21/08 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2201185

A recombinant protein comprises at least one variable region corresponding to an immunoglobulin variable region specific for human Fas and has substantially no more immunogenicity in a human than a human antibody, and is useful in the treatment of autoimmune diseases, especially rheumatism.

Protéine recombinante qui comprend au moins une zone variable correspondant à une zone variable de l'immunoglobuline propre au Fas humain et dont les caractéristiques d'immunogénicité ne sont pas beaucoup plus grandes chez les humains que celles d'un anticorps humain, et qui est utile pour le traitement des maladies auto-immunes, et particulièrement pour le traitement du rhumatisme.

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