Anti-fmd vaccine composition and preparation and use thereof

Details Anti-fmd vaccine composition and preparation and use thereof Anti-fmd vaccine composition and preparation and use thereof

A - Human Necessities

61

K

A61K 39/135 (2006.01) A61P 31/14 (2006.01)

Patent

CA 2741419

A vaccine composition against foot-and-mouth disease and the preparation method thereof are provided. The vaccine comprises the antigenic epitopes of foot-and- mouth disease virus outer capsid protein connected serially in multicopying mode, an immunoglobulin heavy chain constant region or its functional fragments, and a foot-and-mouth disease virus 3D protein or its immunogenic fragments.

La présente invention porte sur une composition vaccinale contre la fièvre aphteuse, ainsi que sur un procédé de préparation de ladite composition. Le vaccin renferme des épitopes antigéniques de la protéine de capside externe du virus de la fièvre aphteuse reliés en série en mode multicopie, une région constante de chaîne lourde dimmunoglobuline ou ses fragments fonctionnels et une protéine 3D du virus de la fièvre aphteuse ou ses fragments immunogènes.

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