Anti-fungal cyclic depsipeptides

Details Anti-fungal cyclic depsipeptides Anti-fungal cyclic depsipeptides

C - Chemistry, Metallurgy

07

K

C07K 11/02 (2006.01) A61K 38/15 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2189129

Compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein R1, R2, X1, X2, X3, X4, X5, X6, X7, and X8, as set forth herein are described. These compounds are useful as agents in the treatment of fungal infections.

L'invention concerne les composés de la formule I, ainsi que leurs sels acceptables sur le plan pharmaceutique. Dans cette formule, R¿1?, R¿2?, X¿1?, X¿2?, X¿3?, X¿4?, X¿5?, X¿6?, X¿7? et X¿8? ont la notation donnée dans la description. Ces composés sont utiles pour le traitement des mycoses.

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