Anti-fungal d-amino acid histatin-based peptides

Details Anti-fungal d-amino acid histatin-based peptides Anti-fungal d-amino acid histatin-based peptides

C - Chemistry, Metallurgy

07

K

C07K 14/47 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) C07K 7/04 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2221780

D-amino acid histatins and histatin-based peptides and methods for treatment of fungal or bacterial infection are described. These D-amino acid histatins and histatin-based peptides are longer-acting anti-fungal or anti-bacterial agents than their L-enantiomeric analogues.

L'invention porte sur des histatines à D-aminoacides et des peptides à base desdites histatines, ainsi que des procédés utilisés pour le traitement d'infections mycosiques ou bactériennes. Lesdits histatines et peptides sont des agents antifongiques et antibactériens à plus longue durée d'action que leurs analogues L-énantiomères.

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