Anti-gd2 antibodies and methods and uses related thereto

Details Anti-gd2 antibodies and methods and uses related thereto Anti-gd2 antibodies and methods and uses related thereto

C - Chemistry, Metallurgy

07

K

C07K 16/30 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2729499

Described herein are antibodies that specifically bind ganglioside GD2. Also described are nucleotides encoding such antibodies, cells expressing such antibodies, methods of use for such antibodies, and methods for using the antibodies to treat diseases associated with ganglioside GD2. In addition, tissue culture media supplements are described as are methods of use for the supplements. Described herein are albumin-ganglioside conjugates and corresponding methods for producing such conjugates. Methods of purifying or isolating antibodies are also described.

La présente invention concerne des anticorps qui se lient spécifiquement au ganglioside GD2. La présente invention concerne en outre des nucléotides codant pour de tels anticorps, des cellules exprimant de tels anticorps, des procédés dutilisation de tels anticorps, et des procédés dutilisation des anticorps pour traiter des maladies associées au ganglioside GD2. La présente invention concerne en outre des suppléments de milieux de culture de tissu ainsi que des procédés dutilisation des suppléments. La présente invention concerne en outre des conjugués albumine-ganglioside et des procédés correspondants pour produire de tels conjugués. La présente invention concerne en outre des procédés de purification ou disolement danticorps.

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