Anti-ghrelin antibodies

Details Anti-ghrelin antibodies Anti-ghrelin antibodies

C - Chemistry, Metallurgy

07

K

C07K 16/26 (2006.01) A61K 39/395 (2006.01) C07K 14/60 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/13 (2006.01) C12N 15/68 (2006.01)

Patent

CA 2569235

Monoclonal antibodies, including humanized antibodies, which bind acylated and unacylated human ghrelin are disclosed. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies of the invention are useful for neutralizing ghrelin activity, e.g., in a human subject suffering from a disorder in which ghrelin activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant anti- ghrelin antibodies are also encompassed by the invention.

L'invention décrit des anticorps monoclonaux, y compris des anticorps humanisés, qui lient la ghreline humaine acylée et non acylée. Un anticorps de l'invention peut être un anticorps pleine longueur ou une portion de celui-ci de liaison à l'antigène. Les anticorps de l'invention sont utiles pour la neutralisation de l'activité de ghreline, par exemple chez un sujet humain souffrant d'un trouble dans lequel l'activité de ghreline est nuisible. La présente invention a également trait à des acides nucléiques, des vecteurs et des cellules hôtes pour l'expression d'anticorps anti-ghreline recombinants.

Affiliated with

Also associated with

Rating

Anti-ghrelin antibodies does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Anti-ghrelin antibodies, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-ghrelin antibodies will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1927496