A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/02 (2006.01) A01N 43/04 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01)
Patent
CA 2289253
The subject of the invention is the use of an immunogenic agent derived from Helicobacter, in the manufacture of a pharmaceutical composition intended for the induction of a T helper 1 (Th1) type immune response against Helicobacter, to prevent or treat a Helicobacter infection in a mammal. This is in particular achieved when the pharmaceutical composition is intended to be administered by the systemic or parenteral route, for example, in the part of the mammal situated under its diaphragm. Also included in the invention is a mucosal/parenteral immunization method for the prevention or treatment of Helicobacter infection.
L'invention porte sur l'utilisation d'un agent immunogène dérivant de l'Helicobacter dans la fabrication de préparations pharmaceutiques suscitant une réponse immunitaire du type T-1 (Th1) anti Helicobacter afin de prévenir ou traiter une infection par l'Helicobacter chez un mammifère. On y parvient en particulier lorsqu'on envisage d'administrer la composition par voie générale ou parentérale par exemple dans la région du mammifère située sous le diaphragme. L'invention porte également sur un procédé combiné d'immunisation, par les muqueuses/parentérale, pour prévenir ou traiter les infections par l'Helicobacter.
Guy Bruno
Haensler Jean
Lee Cynthia K.
Monath Thomas P.
Weltzin Richard A.
Mbm & Co.
Merieux Oravax
LandOfFree
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