Anti-hepcidin antibodies and uses thereof

Details Anti-hepcidin antibodies and uses thereof Anti-hepcidin antibodies and uses thereof

C - Chemistry, Metallurgy

07

K

C07K 16/18 (2006.01)

Patent

CA 2704527

Monoclonal antibodies are provided that selectively bind human hepcidin-25 and are characterized as having high affinity for human hepcidin-25 and strong human mature hepcidin neutralizing properties. The antibodies of the invention are useful therapeutically for increasing serum iron levels, reticulocyte count, red blood cell count, hemoglobin, and/or hematocrit in a human and for the treatment and diagnosis of mature hepcidin-promoted disorders such as anemia, in a human subject.

L'invention porte sur des anticorps monoclonaux se fixant sélectivement sur l'hepcidine-25 humaine et se caractérisant par leur forte affinité pour l'hepcidine-25 humaine et leurs fortes propriétés de neutralisation de l'hepcidine mûre. Lesdits anticorps sont thérapeutiquement utiles pour accroître les niveaux de fer sérique, la numération des réticulocytes, la numération des érythrocytes, l'hémoglobine, et/ou les hématocrites chez l'homme et pour le traitement et le diagnostic de troubles médiés par l'hepcidine mûre, tels que l'anémie chez l'homme.

Affiliated with

Also associated with

Rating

Anti-hepcidin antibodies and uses thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Anti-hepcidin antibodies and uses thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-hepcidin antibodies and uses thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1717931