C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/28 (2006.01) A61K 39/395 (2006.01) C07K 16/32 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2481515
The present invention concerns novel antibody variants, particularly anti-HER2 antibody variants having substitutions at positions within the variable domains of the heavy and light chains.
La présente invention se rapporte à de nouveaux variants d'anticorps, notamment des variants d'anticorps anti-HER-2 comportant des substitutions en des positions appartenant à des domaines variables des chaînes lourdes et des chaînes légères.
Carter Paul J.
Gerstner Resi B.
Lowman Henry B.
Genentech Inc.
Smart & Biggar
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