Anti-hiv agent

Details Anti-hiv agent Anti-hiv agent

C - Chemistry, Metallurgy

07

K

C07K 14/795 (2006.01) A61K 31/40 (2006.01) A61K 31/555 (2006.01) A61K 38/41 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07D 487/22 (2006.01) C07F 1/08 (2006.01) C07F 15/02 (2006.01) C07K 1/113 (2006.01) C07K 14/765 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2113837

ABSTRACT The invention relates to an anti-HIV agent comprising, as an active ingredient, at least one porphyrin derivative selected from the following derivatives (A) and (B): (A) porphyrins modified with a compound selected from carbodiimides, alkylenediamines and alcohols; and (B) complexes of a plasma protein or a chemically modified plasma protein and a porphyrin which may have been modified with a compound selected from carbodiimides, alkylenediamines and alcohols. This anti-HIV agent is excellent in killing effect on HIV-infected cells, inhibitory effect on cytopathy due to HIV infection and HIV-replication inhibiting effect, and high in safety. The agent is hence useful as agents for the prophylaxis and treatment of AIDS.

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