Anti-hiv and anti-tumor peptides and fragments of lysozyme

Details Anti-hiv and anti-tumor peptides and fragments of lysozyme Anti-hiv and anti-tumor peptides and fragments of lysozyme

A - Human Necessities

61

K

A61K 38/04 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 38/47 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2415083

A fragment of lysozyme which contains a minimum nine amino acid sequence with antiviral, anti-tumor and bactericidal activities but lacking muramidase activity is provided. The invention also relates to pharmaceutical compositions containing this fragment and methods for treating HIV infection or for inhibiting tumor growth using this fragment as an active ingredient.

L'invention concerne un fragment de lysozyme contenant une séquence d'au moins neuf résidus d'acides aminés. Ce fragment est doté d'une activité antivirale, antitumorale et bactéricide sans toutefois présenter l'activité muramidase du lysozyme. L'invention concerne également des compositions pharmaceutiques contenant ce fragment, ainsi que des méthodes permettant de traiter l'infection à VIH ou d'inhiber la croissance tumorale à l'aide ce fragment, lequel est utilisé comme ingrédient actif.

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