Anti-hiv benzamide compounds

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/497 (2006.01) A61K 31/33 (2006.01)

Patent

CA 2527211

The invention provides a therapeutic method for preventing or treating a pathological condition or symptom in a mammal, such as a human, wherein the infectivity of a pathogen such as a retrovirus toward mammalian cells is implicated and inhibition of its infectivity is desired comprising administering to a mammal in need of such therapy, an effective amount of an N- benzamide derivative of a piperazinyl amide of an amino thereof that inhibits pathogenic infectivity, including pharmaceutically acceptable salts thereof.

La présente invention concerne une méthode thérapeutique de prévention ou de traitement d'une condition ou d'un symptôme pathologique chez un mammifère, tel qu'un homme, pour lequel l'infectivité d'un pathogène tel qu'un rétrovirus à l'égard des cellules de mammifère est impliquée et pour lequel l'inhibition de ladite infectivité est désirée. Cette méthode consiste à administrer à un mammifère nécessitant un tel traitement, une quantité efficace d'un dérivé N-benzamide d'un amide pipérazinyle d'un amino de ce dernier qui présente une infectivité pathogène, y compris ses sels pharmaceutiquement acceptables.

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