A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/675 (2006.01) A61K 31/505 (2006.01) A61K 31/51 (2006.01)
Patent
CA 2180732
An anti-HIV drug, anti-HIV activity synergist, and AIDS preventive and remedy, each containing as the active ingredient a vitamin B1 derivative such as thiamin disulfide, bisbentiamine, bisbutythiamin, bisibutiamine, alitiamin, fursultiamine or octotiamine, or a salt thereof. These drugs are useful for preventing and treating AIDS, because they have the effect of inhibiting the growth of HIV on early infected cells without killing the cells and both of the cytocidal and HIV-killing effects on the cells that have come to produce HIV continuously.
L'invention concerne un médicament anti-VIH, un produit synergique d'activité anti-VIH, ainsi qu'un préventif et un remède contre le SIDA, chacun contenant comme ingrédient actif un dérivé de la vitamine B¿1? tel que le bisulfure de thiamine, la bisbentiamine, la bisbutythiamine, la bisibutiamine, l'alitiamine, la fursultiamine ou l'octotiamine, ou un sel de ceux-ci. Ces médicaments sont utiles dans la prévention et le traitement du SIDA, puisqu'il présentent l'effet d'inhiber la croissance du VIH sur des cellules précocement infectées sans tuer les cellules, ainsi que des effets à la fois cytocide et annihilant le VIH sur les cellules au stade de production continu du VIH.
Shoji Shozo
Tachibana Kuniomi
Gowling Lafleur Henderson Llp
Nissui Pharmaceutical Co. Ltd.
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