C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/46 (2006.01) A61K 39/395 (2006.01) A61P 19/08 (2006.01) A61P 29/00 (2006.01) A61P 31/00 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) C12P 21/08 (2006.01)
Patent
CA 2657133
An antibody specifically recognizing human .alpha.9 integrin (in particular, a monoclonal antibody); a chimeric antibody, a humanized antibody and a human antibody; a hybridoma cell producing the monoclonal antibody as described above; a method of producing the monoclonal antibody as described above; a method of producing the hybridoma cell as described above; a therapeutic containing the antihuman .alpha.9 integrin antibody as described above; a diagnostic containing the antihuman .alpha.9 integrin antibody as described above; a method of screening a compound inhibiting the activity of human .alpha.9 integrin; and so on.
La présente invention concerne un anticorps reconnaissant de façon spécifique l'intégrine .alpha.-9 humaine (en particulier un anticorps monoclonal) ; un anticorps chimérique, un anticorps humanisé et un anticorps humain ; une cellule hybridome produisant l'anticorps monoclonal comme décrit plus haut ; un procédé de production de l'anticorps monoclonal comme décrit plus haut ; un procédé de production de la cellule hybridome comme décrit plus haut ; un produit thérapeutique contenant l'anticorps anti-intégrine .alpha.-9 humaine comme décrit plus haut ; une trousse de diagnostic contenant l'anticorps anti-intégrine .alpha.-9 humaine comme décrit plus haut ; un procédé de criblage permettant de détecter un composé inhibant l'activité de l'intégrine .alpha.-9 humaine ; et ainsi de suite.
Kanayama Masashi
Kon Shigeyuki
Kurotaki Daisuke
Uede Toshimitsu
Borden Ladner Gervais Llp
Gene Techno Science Co. Ltd.
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