C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/18 (2006.01) A61K 39/395 (2006.01) A61P 35/00 (2006.01) C12N 5/10 (2006.01) C12N 15/02 (2006.01) C12P 21/08 (2006.01) G01N 33/574 (2006.01)
Patent
CA 2669731
Disclosed are: an antibody capable of reacting specifically with hDlk-1 and shows an anti-tumor activity in vivo (an anti-hDlk-1 antibody); a fragment of the antibody; a hybridoma capable of producing the antibody; a complex of the antibody or a fragment thereof and a physiologically active substance; a pharmaceutical composition, a therapeutic agent for a tumor, a tumor angiogenesis inhibitor or a diagnostic agent for a tumor, which comprises the antibody or the like; a method for the detection of a tumor; a kit for the detection and/or diagnosis of a tumor; and others.
La présente invention concerne : un anticorps capable de réagir spécifiquement avec le gène hDlk1 et doté d'une activité anti-tumorale in vivo (un anticorps anti-hDlk1) ; un fragment de l'anticorps ; un hybridome capable de produire l'anticorps ; un complexe de l'anticorps ou d'un fragment de celui-ci et d'une substance physiologiquement active ; une composition pharmaceutique, un agent thérapeutique pour une tumeur, un inhibiteur de l'angiogenèse tumorale ou un agent diagnostique pour une tumeur, qui contiennent l'anticorps ou un analogue ; un procédé de détection d'une tumeur ; une trousse de détection et/ou de diagnostic d'une tumeur ; et d'autres éléments associés.
Nakamura Koji
Tajima Rie
Fetherstonhaugh & Co.
Livtech Inc.
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