C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2095926
Humanised antibody molecules (HAMs) are described having specificity for human milk fat globate and having an anti- gen binding site wherein at least one of the complementarity determining regions (CDRs) of the variable domains is derived from the mouse monoclonal antibody CTMO1 and the remaining immunoglobulin-derived parts of the HAM are derived from a hu- man immunoglobulin. The HAMs maybe chimeric humanised antibodies or CDR- grafted humanised antibodies and are prefer- ably produced by recombinant DNA techniques. The HAMs may be conjugated to an effector or reporter molecule, particularly methyltrithio anti-tumour agents, and are useful for in vivo diagnosis and therapy.
Adair John Robert
Baker Terence Seward
Hamann Philip R.
Hinman Lois M.
Lyons Alan Howard
Celltech Limited
Celltech Therapeutics Limited
Kirby Eades Gale Baker
LandOfFree
Anti-human milk fat globule humanised antibodies does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Anti-human milk fat globule humanised antibodies, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-human milk fat globule humanised antibodies will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1820924