Anti-human mp52 monoclonal antibody

Details Anti-human mp52 monoclonal antibody Anti-human mp52 monoclonal antibody

C - Chemistry, Metallurgy

12

N

C12N 5/18 (2006.01) C07K 14/51 (2006.01) C07K 16/22 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2254857

A mouse anti-human MP52 monoclonal antibody which binds to dimeric human MP52 but not to monomeric human MP52. This mouse monoclonal antibody comprising IgG and having a high specificity can be obtained by sensitizing mice with human MP52 (CHO-MP52) produced in CHO cells and human MP52 (rhMP52) produced in escherichia coli. This antibody is useful in, for example, purifying or assaying human MP52 produced by genetic engineering techniques.

Anticorps monoclonal de souris anti-MP52 humaine, qui se lie à la MP52 humaine dimère, mais non à la MP52 monomère. On peut obtenir cet anticorps de souris contenant des IgG et ayant une forte spécificité en sensibilisant des souris avec des MP52 humaines (CHO-MP52) produites dans des cellules CHO et des MP52 humaines (rhMP52) produites chez Escherichia coli. Cet anticorps est utile pour, par exemple, purifier ou cribler la MP52 humaine produite par des techniques de génie génétique.

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