Anti-human plasmin-.alpha.2- plasmin inhibitor complex...

C - Chemistry – Metallurgy – 12 – P

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C12P 21/08 (2006.01) C07K 16/38 (2006.01) C07K 16/40 (2006.01) C12N 5/18 (2006.01) G01N 33/573 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2075937

A first monoclonal antibody which specifically reacts with a human .alpha.2-plasmin inhibitor complex (PIC) and a human plasminogen; a second monoclonal antibody which reacts with PIC and also with a human .alpha.2-plasmin inhibitor; a third monoclonal antibody which reacts with PIC, but does not react with a human plasminogen and a human .alpha.2-plasmin inhibitor; hybridomas which secrete the first to third monoclonal antibodies, and an immunoassay using the first to third monoclonal antibodies.

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