Anti-human pulmonary adenocarcinoma specific monoclonal...

Details Anti-human pulmonary adenocarcinoma specific monoclonal... Anti-human pulmonary adenocarcinoma specific monoclonal...

C - Chemistry, Metallurgy

12

P

167/37, 195/1.10

C12P 21/08 (2006.01) A61K 39/395 (2006.01) A61K 47/42 (2006.01) C07K 16/30 (2006.01) G01N 33/574 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1306707

ABSTRACT OF THE DISCLOSURE Monoclonal antibodies specific for human pulmonary adenocarcinoma recognizing sialylated glycoproteins or glycolipids as antigens but not reactive with normal human lung tissue. Hybridomas having the characteristics of cell line ALC-186 secrete such antibodies. Methods of diagnosing human pulmonary adenocarcinoma by immunoassay, immunohistochemical staining and methods of therapeutic treatment are described.

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