Anti-human tenascin monoclonal antibody

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 16/30 (2006.01)

Patent

CA 2558718

An anti-human tenascin monoclonal antibody is described, whose light and heavy chain variable region sequences are SEQ ID NO: 1 and SEQ ID NO: 2, respectively, its proteolytic fragments capable of binding to an antigenic epitope within the region A(1-4)-D of human tenascin, its recombinant derivatives, its conjugates and its similar functional analogues capable of binding to an antigenic epitope within the A(1-4)-D region of human tenascin.

L'invention concerne un anticorps monoclonal anti-tenascine humaine, dont les séquences régionales variables à chaîne légère et lourde sont, respectivement, SEQ ID NO: 1 et SEQ ID NO: 2, ainsi que ses fragments protéolytiques pouvant être liés à un épitope antigénique dans la région A¿(1-4)?-D de la tenascine humaine, ses dérivés de recombinaison, ses conjugués et ses analogues fonctionnels semblables pouvant être liés à un épitope antigénique dans la région A¿(1-4)?-D de la ténascine humaine.

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