Anti-hypercholesterolemic compounds

Details Anti-hypercholesterolemic compounds Anti-hypercholesterolemic compounds

C - Chemistry, Metallurgy

07

H

C07H 15/26 (2006.01) A61K 31/397 (2006.01) A61K 31/7052 (2006.01) A61P 3/06 (2006.01) A61P 9/10 (2006.01) C07D 205/08 (2006.01) C07H 7/033 (2006.01)

Patent

CA 2550373

This invention provides cholesterol absorption inhibitors of formula (I), and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating and preventin atherosclerosis and atherosclerotic disease events.

L'invention porte sur des inhibiteurs d'absorption du cholestérol de formule (I) et sur leurs sels et esters pharmacocompatibles. Lesdits composés s'avèrent utiles pour abaisser les niveaux plasmiques des cholestérols, et en particulier du cholestérol LDL, et traiter et prévenir l'athérosclérose et les troubles athérosclérotiques.

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