C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 7/06 (2006.01) A61K 31/7052 (2006.01) A61P 3/06 (2006.01) A61P 9/10 (2006.01) C07H 7/00 (2006.01)
Patent
CA 2611142
This invention provides cholesterol absorption inhibitors of Formula (I), and the pharmaceutically acceptable salts and esters thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating and preventing atherosclerosis and atherosclerotic disease events.
L'invention concerne des inhibiteurs d'absorption de cholestérol représentés par la formule (I), et des sels et des esters de ceux-ci pharmaceutiquement acceptables. Ces composés sont utilisés pour abaisser les niveaux de cholestérol plasmique, en particulier du cholestérol LDL, et pour traiter ou prévenir l'athérosclérose et des événements de maladies athérosclérotiques.
Devita Robert J.
Morriello Greg J.
Ogawa Anthony K.
Ujjainwalla Feroze
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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