C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 205/08 (2006.01) A61K 31/397 (2006.01) A61P 3/06 (2006.01) C07D 405/12 (2006.01)
Patent
CA 2672221
This invention provides cholesterol absorption inhibitors of Formula I : I and the pharmaceutically acceptable salts thereof. The compounds are useful for lowering plasma cholesterol levels, particularly LDL cholesterol, and for treating and preventing atherosclerosis and atherosclerotic disease events.
Cette invention porte sur des inhibiteurs de l'absorption du cholestérol, représentés par la Formule I : I et sur les sels pharmaceutiquement acceptables de ces inhibiteurs. Ces composés sont utiles pour diminuer les taux de cholestérol dans le plasma, en particulier le cholestérol LDL, et pour traiter et prévenir l'athérosclérose et les événements pathologiques athérosclérotiques.
Devita Robert J.
Lin Peter
Morriello Gregori J.
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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