Anti-hypertensive agent

Details Anti-hypertensive agent Anti-hypertensive agent

A - Human Necessities

61

K

A61K 38/00 (2006.01) A61P 9/12 (2006.01)

Patent

CA 2695666

Disclosed is an anti-hypertensive agent. The anti-hypertensive agent comprises at least one peptide selected from the group consisting of peptides respectively comprising the amino acid sequences (1) to (6) which are derived from a globin protein digest or a globin protein digest containing at least one of the above- mentioned peptides as an active ingredient: (1) Val-Val-Tyr-Pro (SEQ ID NO: 1); (2) Trp-Gly-Lys-Val-Asn (SEQ ID NO:2); (3) Trp-Gly-Lys-Val (SEQ ID NO:3); (4) Trp-Gly-Lys (SEQ ID NO:4); (5) Ala-Ala-Trp-Gly-Lys (SEQ ID NO:5); and (6) Phe-Glu-Ser (SEQ ID NO:6).

Cette invention se rapporte à un agent antihypertenseur. L'agent antihypertenseur comprend au moins un peptide sélectionné dans le groupe constitué par les peptides comprenant respectivement les séquences d'acides aminés (1) à (6) qui proviennent d'un digesté de globine ou d'un digesté de globine contenant au moins l'un des peptides mentionnés ci-dessus comme principe actif : (1) Val-Val-Tyr-Pro (SEQ ID NO : 1) ; (2) Trp-Gly-Lys-Val-Asn (SEQ ID NO : 2) ; (3) Trp-Gly-Lys-Val (SEQ ID NO : 3) ; (4) Trp-Gly-Lys (SEQ ID NO : 4) ; (5) Ala-Ala-Trp-Gly-Lys (SEQ ID NO : 5) ; et (6) Phe-Glu-Ser (SEQ ID NO : 6).

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