Anti-idiotypic antibodies which induce an immune response...

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/42 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2177328

The present invention relates to anti-idiotypic antibodies which induce an immune response against tumors, bearing as antigen the epidermal growth factor receptor (EGFR). The antibodies of the invention may mimick said antigen. As preferred embodiment the antibodies of the invention derive from mAb 425 (ATCC HB 9629) or a humanized or chimeric derivative thereof.

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