Anti-il 17a/il-17f cross-reactive antibodies and methods of...

Details Anti-il 17a/il-17f cross-reactive antibodies and methods of... Anti-il 17a/il-17f cross-reactive antibodies and methods of...

C - Chemistry, Metallurgy

07

K

C07K 16/24 (2006.01) A61K 39/395 (2006.01) A61P 37/02 (2006.01)

Patent

CA 2721713

This invention provides fully human monoclonal antibodies that recognize IL- 17F, the IL- 17F homodimer, IL--17A, the IL- 17A homodimer, and/or the heterodimeric IL- 17A/IL-17F protein complex. The invention further provides methods of using such monoclonal antibodies as a therapeutic, diagnostic, and prophylactic.

Cette invention porte sur des anticorps monoclonaux entièrement humains qui reconnaissent IL-17F, l'homodimère IL-17F, IL-17A, l'homodimère IL-17A et/ou le complexe protéique IL-17A/IL-17F hétérodimérique. L'invention porte, en outre, sur des procédés d'utilisation de tels anticorps monoclonaux en tant que produits thérapeutiques, diagnostiques et prophylactiques.

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