Anti-il-17f antibodies and methods of use thereof

A - Human Necessities – 61 – K

Patent

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A61K 38/00 (2006.01) C07K 14/54 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2759848

This invention provides fully human monoclonal antibodies that recognize IL-17F and/or the heterodimeric IL-17A/IL-17F complex, but do not recognize IL-17A. The invention further provides methods of using such monoclonal antibodies as a therapeutic, diagnostic, and prophylactic.

Cette invention concerne des anticorps monoclonaux entièrement humains qui reconnaissent l'interleukine IL- 17F et/ou le complexe d'hétérodimères IL-17A/IL-17F, mais qui ne reconnaissent pas l'interleukine IL-17A. L'invention concerne par ailleurs des méthodes d'utilisation de ces anticorps monoclonaux comme agents thérapeutiques, diagnostiques et prophylactiques.

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