Anti-il-1r1 single domain antibodies and therapeutic uses

Details Anti-il-1r1 single domain antibodies and therapeutic uses Anti-il-1r1 single domain antibodies and therapeutic uses

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 47/48 (2006.01) A61P 11/00 (2006.01) C07K 16/44 (2006.01)

Patent

CA 2588892

Disclosed is the use of an antagonist of Interleukin 1 receptor type 1 (IL- 1R1) for the manufacture of a medicament treating, preventing or suppressing lung inflammation or a respiratory disease. In some embodiments of the described invention, the medicament is for local administration to pulmonary tissue. Also disclosed are methods for treating lung inflammation or a respiratory disease.

L'invention concerne l'utilisation d'un antagoniste du récepteur de l'interleukine 1 de type 1 (IL-1R1) dans la fabrication d'un médicament permettant de traiter, prévenir ou inhiber l'inflammation pulmonaire ou une maladie respiratoire. Dans certains modes de réalisation, le médicament est administré par voie orale à un tissu pulmonaire. L'invention porte également sur des procédés de traitement d'une inflammation pulmonaire ou d'une maladie respiratoire.

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