Anti-il-20 antibody and its use in treating il-20 associated...

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 16/00 (2006.01) A61K 51/00 (2006.01) C07K 16/24 (2006.01) C12P 21/04 (2006.01)

Patent

CA 2691892

This invention features an antibody specifically binding to human IL-20 (e.g., mAb 7E and a equivalent thereof) and its use in treating an IL-20 associated inflammatory disease, such as atherosclerosis, RA, psoriasis, psoriatic arthritis, bacteria-induced gastric ulcer, and acute renal failure.

L'invention concerne un anticorps se liant spécifiquement à IL-20 humain (par exemple, mAb 7E et un équivalent de celui-ci) et son utilisation dans le traitement d'une maladie inflammatoire associée IL-20, telle que l'athérosclérose, la polyarthrite rhumatoïde (PR), le psoriasis, l'arthrite psoriasique, l'ulcère gastrique induit par des bactéries et une insuffisance rénale aiguë.

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