Anti-il-20 receptor antibodies and binding partners and...

Details Anti-il-20 receptor antibodies and binding partners and... Anti-il-20 receptor antibodies and binding partners and...

C - Chemistry, Metallurgy

07

K

C07K 16/24 (2006.01) A61K 38/20 (2006.01)

Patent

CA 2542546

The present invention relates to blocking the activity of IL-20 receptor polypeptide molecules. IL-20 is a cytokine that is involved in inflammatory processes and human disease. IL-20RA/IL-20RB is a common receptor for IL-20. The present invention includes anti-IL-20 receptor antibodies and binding partners, including anti-IL-20RA, anti-IL-20RB and anti-IL-20RA/IL-20RB antibodies as well as methods for antagonizing IL-20RA and IL-20RB, either individually or together, using such antibodies and binding partners.

L'invention concerne le blocage de l'activité des molécules du polypeptide du récepteur IL-20. IL-20 est une cytokine qui est impliquée dans des procédés inflammatoires et des maladies chez l'homme. L-20RA/IL-20RB est un récepteur commun de IL-20. Cette invention porte sur des anticorps du récepteur anti-IL-20 et sur des partenaires de liaison, y compris des anticorps anti-IL-20RA, anti-IL-20RB et anti-IL-20RA/IL-20RB, ainsi que sur des procédés d'antagonisation de IL-20RA et IL-20RB, soit individuellement, soit ensemble, au moyen de ces anticorps et de ces partenaires de liaison.

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