A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/5375 (2006.01) A61K 9/00 (2006.01) A61K 31/137 (2006.01) A61K 31/4196 (2006.01) A61K 31/4418 (2006.01) A61K 31/496 (2006.01) A61P 31/10 (2006.01) A61K 47/30 (2006.01)
Patent
CA 2402267
The invention relates to a preparation containing an active substance combination comprised of a topical antimycotic agent, of a systemic antimycotic agent, and of a physiologically safe lacquer base. The inventive preparation is suited for treating onychomycoses. The invention preferably uses water-insoluble lacquer preparations and a combination of at least one systemic antimycotic agent from the group containing itraconazole, terbinafine, fluconazole or the salts thereof with at least one topical antimycotic agent from the group containing ciclopirox 6-(2,4,4- trimethylpentyl)-1-hydroxy-4-methyl-2 (1H)-pyridone, amorolfine and butenafine or the salts thereof.
L'invention concerne une préparation contenant une combinaison de principes actifs à base d'un antimycotique topique et d'un antimycotique systémique et d'une base de vernis physiologiquement tolérable, qui s'utilise pour traiter des onychomycoses. On utilise de préférence des préparations de vernis non solubles dans l'eau et une combinaison d'au moins un antimycotique systémique du groupe comprenant itraconazol, terbinafine et fluconazol ou leurs sels avec au moins un antimycotique topique du groupe comprenant ciclopirox, 6-(2,4,4-triméthylpentyl)-1-hydroxy-4-méthyl-2(1H)-pyridone, amorolfine et buténafine ou leurs sels.
Bohn Manfred
Kraemer Karl Theodor
Aventis Pharma Deutschland Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis Deutschland Gmbh
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