Anti-infective agents useful against multidrug-resistant...

C - Chemistry – Metallurgy – 07 – H

Patent

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Details

C07H 17/08 (2006.01) A61K 31/335 (2006.01) A61K 31/7048 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2398848

The invention relates to novel methods for using macrolide anti-infective agents. The macrolide anti-infective agents demonstrate antibacterial activity against multi-drug resistant strains of bacteria and, in particular, methicillin-resistant Staphylo-coccus aureus (MRSA). Methods for inhibiting the activity of multi-drug resistant bacterial organisms and methods for treating a bacterial infection caused by such organisms are described herein.

La présente invention concerne des nouvelles méthodes d'utilisation d'agents anti-infectieux macrolides. Ces agents présentent une activité antibactérienne contre des souches de bactéries résistant à l'action de plusieurs médicaments et en particulier contre des <i>Staphylococcus aureus</i> (MRSA) résistant à la méthicilline. L'invention concerne également des méthodes permettant d'inhiber l'activité d'organismes bactériens résistant à l'action de plusieurs médicaments et des méthodes de traitement d'une infection bactérienne engendrée par de tels organismes.

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