Anti-infective and lubricious medical articles and method...

A - Human Necessities – 61 – L

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A61L 29/00 (2006.01) A61L 29/06 (2006.01) A61L 29/08 (2006.01) A61L 29/16 (2006.01) A61L 31/00 (2006.01)

Patent

CA 2004367

A substantially hydrophilic polymeric medical article has a coating of chlorhexidine and a silicone on its surface and may have chlorhexidine bulk distributed throughout the polymer. The invention includes a method for preparing the article which includes dipping the article into a solution of chlorhexidine and silicone in a solvent. The method may also include preparing a melt of a substantially hydrophilic polymer having bulk distributed chlorhexidine by twin screw compounding a mixture of polymer and chlorhexidine and extruding the melt into the shape of the desired article prior to applying the coating.

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