Anti-inflammatory 1-phenylethanolamine derivatives,...

C - Chemistry – Metallurgy – 07 – C

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C07C 233/12 (2006.01)

Patent

CA 1108183

ABSTRACT The invention relates to topically anti- inflammatory 1-phenylethanolamine derivatives of the general formula I:- Image I or acid-addition salts thereof, to pharmaceutical compositions thereof, and to analogy processes for their manufacture. A representative compound is 1-(4-amino-3,5-dichlorophenyl)-2-[1,1-dimethyl-2- (2-phenylacetamido)ethylamino]ethanol. The derivatives are useful in particular for the treatment of inflammatory diseases or conditions of the skin.

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