C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 223/10 (2006.01) A61K 31/55 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2576257
The invention provides compounds, compositions and uses of compounds of general formula (I) or pharmaceutically acceptable salts thereof, which are 3- aminocaprolactam derivatives, for the preparation of a medicament intended to treat an inflammatory disorder wherein X is -CO-Y-(R1)n or SO2-Y-(R1)n; and Y is 0 cycloalkyl or polycyloalkyl group (such as an adamantyl, adamantanemethyl, bicyclooctyl, cyclohexyl, cyclopropyl group); or is 0 cycloalkenyl or polycycloalkenyl group.
L'invention concerne des composés, des compositions et les utilisations de ces composés, de formule générale (I), y compris le sels pharmaceutiquement acceptables correspondants, qui sont des dérivés de 3-aminocaprolactame, pour la préparation d'un médicament capable de traiter un trouble anti-inflammatoire. Dans cette formule, X est -CO-Y-(R1)n ou SO2-Y-(R1)n; et Y est un groupe cycloalkyle ou polycyloalkyle (du type groupe adamantyle, adamantaneméthyle, bicyclooctyle, cyclohexyle, cyclopropyle); ou bien un groupe cycloalcényle ou polycycloalcényle.
Fox David John
Grainger David John
Cambridge Enterprise Limited
Sim & Mcburney
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