C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 233/49 (2006.01) A61K 31/198 (2006.01) A61K 31/223 (2006.01) A61P 29/00 (2006.01) A61P 37/02 (2006.01) C07C 231/02 (2006.01) C07C 319/20 (2006.01) C07C 323/59 (2006.01)
Patent
CA 2446944
The present invention ralates to compounds of formula (I): wherein R is hydrogen (H) or c1-6 alkyl; and X is defined such that - NH - (X) - COOH is the residue of an amino acid, which amino acid may itself optionally be substituted at any pendant amino group thereof by a residue of a carboxylic acid or a derivative thereof; or a salt thereof. The use of these compounds, in particular as potential anti-inflammatory and immunomodulatory drugs, and their preparation are described.
L'invention concerne des composés de formule (I), où R est hydrogène (H), ou alkyle C¿1-6?; et X est défini de sorte que - NH - (X)- COOH est le résidu d'un acide aminé, lequel acide aminé peut être éventuellement substitué au niveau de n'importe quel groupe aminé latéral dudit acide par un résidu d'acide carboxylique ou un dérivé de celui-ci; ou un sel de celui-ci. L'invention concerne l'utilisation de ces composés, en particulier, en tant que médicaments anti-inflammatoires et immunomodulateurs, ainsi que leur préparation.
Croda International Plc
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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