Anti-inflammatory composition comprising berry extract

Details Anti-inflammatory composition comprising berry extract Anti-inflammatory composition comprising berry extract

A - Human Necessities

61

K

A61K 36/73 (2006.01) A61K 31/352 (2006.01) A61K 47/10 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) A61P 39/06 (2006.01)

Patent

CA 2622286

A method for deriving compositions having antioxidant and anti-inflammatory activity from berries is provided. The method results in a berry extract compositions having stable anthocyanin content. In one aspect, the method comprises exposing a berry to a solvent composition having a pH of from about 1 to about 4.5, and recovering a berry extract having a stabilized anthocyanin content. The berry may be a blackberry. A cryoprotectant may be added, to further stabilize the anthocyanin content. Compositions comprising the berry extract of the present invention, formulated for oral and/or topical administration, are provided also, including nutritional supplements, capsules, enteric- coated capsules, film-coated capsules, tablets, enteric- coated tablets, film-coated tablets, chewing gums, lotions, creams, mucoadhesive gels, vanishing lotions, vanishing creams, and the like. In yet another aspect, the present invention provides methods and compositions for treating inflammation, oxidative damage, or cancer in a mammal.

L'invention concerne un procédé permettant d'obtenir, à partir de baies, des compositions à activité antioxydante et anti-inflammatoire. Le procédé fournit des compositions d'extraits de baies ayant un contenu d'anthocyanine stable. Suivant un aspect, le procédé comprend l'exposition des baies à une composition de solvant ayant un pH d'environ 1 à environ 4,5, et la récupération d'un extrait de baies à contenu d'anthocyanine stabilisée. Les baies peuvent être des mûres sauvages. Un cryoprotecteur peut être ajouté pour stabiliser davantage le contenu d'anthocyanine. L'invention concerne également des compositions comprenant l'extrait de baies selon l'invention, formulées pour l'administration orale et/ou topique, lesdites compositions comprenant des compléments nutritifs, des capsules à enrobage entérique, des capsules enrobées par pelliculage, des comprimés, des comprimés à enrobage entérique, des comprimés enrobés par pelliculage, des chewing gums, des lotions, des crèmes, des gels mucoadhésifs, des lotions de beauté, des crèmes de beauté et analogues. Suivant un autre aspect, l'invention concerne des procédés et des compositions pour le traitement d'inflammations, de destructions oxydatives ou de cancers chez un mammifère.

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