Anti-inflammatory compositions derived from chicory

Details Anti-inflammatory compositions derived from chicory Anti-inflammatory compositions derived from chicory

A - Human Necessities

61

K

A61K 31/365 (2006.01) A23K 1/14 (2006.01) A23K 1/16 (2006.01) A23K 1/18 (2006.01) A23L 1/212 (2006.01) A23L 1/30 (2006.01) A61K 36/28 (2006.01) A61K 36/48 (2006.01) A61K 36/74 (2006.01) A61K 45/06 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2488279

Compositions capable of reducing a risk of inflammation in a mammal(s) are provided. The compositions contain a therapeutically effective amount of a thermally processed (e.g., extruded) plant material that includes .alpha.- methylene-.gamma.-butyrolactone (.alpha.-MGBL) and/or several structurally related parent phytochemical capable of inhibiting enzymatic and/or transcriptional activity in the mammal, which is believed to treat and/or prevent inflammation. In this regard, the risk of incidence of other disease or ailments which are believed to be caused by inflammation (e.g., chronic inflammation) may be reduced. The phytochemical source can be derived from a single plant material, such as chicory.

Compositions pouvant réduire le risque d'inflammation chez un ou plusieurs mammifères. Lesdites compositions contiennent une dose efficace au plan thérapeutique d'une substance végétale traitée thermiquement (ex. extrudée) contenant de l' alpha -méthylène- gamma -butyrolactone ( alpha -MGBL) et/ou plusieurs phytochimiques parents apparentés au plan structural, pouvant inhiber l'activité enzymatique et/ou transcriptionnelle chez le mammifère, et sensée traiter et/ou prévenir l'inflammation. Ainsi, le risque d'incidence d'autres maladies ou malaises connus pour être induits par l'inflammation (ex.inflammation chronique) peut être réduit. La source de phytochimique peut être dérivée d'une seule substance végétale, comme la chicorée.

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