C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/47 (2006.01) A61K 38/10 (2006.01) A61K 38/17 (2006.01) A61P 29/00 (2006.01) C07K 7/08 (2006.01) C12N 9/12 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2414296
The present invention provides anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of use thereof for treating inflammatory disorders. The present invention also provides methods of identifying anti- inflammatory compounds and methods of inhibiting NF-.kappa.B-dependent target gene expression in a cell.
La présente invention concerne des composés anti-inflammatoires, leurs compositions pharmaceutiques et leurs méthodes d'utilisation en vue d'un traitement de troubles inflammatoires. La présente invention concerne également des méthodes d'identification de composés anti-inflammatoires et des méthodes d'inhibition de l'expression d'un gène cible dépendant de NF-.kappa.B dans une cellule.
Findeis Mark A.
Ghosh Sankar
May Michael J.
Phillips Kathryn
Borden Ladner Gervais Llp
Praecis Pharmaceuticals Incorporated
Yale University
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