Anti-inflammatory furanone compounds

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 407/04 (2006.01) A61K 31/335 (2006.01) A61K 31/38 (2006.01) C07D 307/34 (2006.01) C07D 307/60 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2027863

ABSTRACT ANTI-INFLAMMATORY FURANONE COMPOUNDS New furanone compounds have anti-inflammatory, immunosuppresive and anti-proliferative activity and are useful in treating psoriasis and modifying calcium homeostasis. A compound of the invention is 4-[3,6-dihydro-6-hydroxy-5-(3-phenylpropyl)-2H-pyran-2-yl]-5- hydroxy-2-(5H)-furanone.

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