Anti-inflammatory macrolide

Details Anti-inflammatory macrolide Anti-inflammatory macrolide

C - Chemistry, Metallurgy

07

H

C07H 17/08 (2006.01) A61K 31/7048 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2748847

The compound 3'-N-demethyl-4"-O-(2-diethylaminoethanoyl)-6-O-methyl-9a-aza-9a- homoerythromycin A, having the Formula (I): or a salt thereof, compositions comprising the compound, its use in the treatment of neutrophil dominated in-flammatory diseases, and methods for its preparation.

La présente invention porte sur le composé 3'-N-déméthyl-4''-O-(2-diéthylaminoéthanoyl)-6-O-méthyl-9a-aza-9a-homoérythromycine A, répondant à la formule (I) ou un sel de celui-ci, sur des compositions comprenant le composé, sur ses utilisations pour le traitement de maladies inflammatoires dominées par les neutrophiles et sur ses procédés de préparation.

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