C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/407 (2006.01) A61P 29/00 (2006.01)
Patent
CA 2391871
The present invention relates to compounds of the formula I <see formula I> in which one of the radicals R8 and R9 is a hydrogen atom or an alkyl group and the other is hydroxyl, alkoxy or acyloxy or where R8 and R9, together with the carbon atom to which they are bonded, are a carbonyl group and the radicals R1 to R7 have the meanings indicated in the description. The compounds inhibit the release of various mediators of the arachidonic acid cascade and can thus be used for the prevention of allergically induced disorders or for the treatment of disorders of the rheumatic type.
L'invention concerne des composés de formule (I), dans laquelle l'un des radicaux R8 et R9 désigne un atome d'hydrogène ou un groupe alkyle, et l'autre, un groupe hydroxyle, alcoxy ou acyloxy, ou bien R8 et R9 représentent, conjointement avec un atome de carbone auquel ils sont liés, un groupe carbonyle, les radicaux R1 à R7 ayant les significations données dans la description. Les composés précités inhibent la libération de différents médiateurs de cascade d'acide arachidonique et conviennent ainsi pour la prévention de maladies d'origine allergique ou pour le traitement d'affections de forme rhumatismale.
Laufer Stefan
Striegel Hans-Gunter
Tollmann Karola
Deeth Williams Wall Llp
Merckle Gmbh
LandOfFree
Anti-inflammatory oxo derivatives and hydroxy derivatives of... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Anti-inflammatory oxo derivatives and hydroxy derivatives of..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-inflammatory oxo derivatives and hydroxy derivatives of... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1403480