Anti-inflammatory peptide analogs and treatment to inhibit...

Details Anti-inflammatory peptide analogs and treatment to inhibit... Anti-inflammatory peptide analogs and treatment to inhibit...

C - Chemistry, Metallurgy

07

K

C07K 7/08 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) C07K 7/06 (2006.01) C07K 14/575 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2140907

Small, anti-inflammatory compounds that are peptide analogs are described useful to inhibit inflammation of a mammal's skin, mucous membranes, or lacerations of the musculature or injury to the brain or leakage of fluids into the air spaces of the lungs. Peptide analogs of the invention have the primary sequence TN-A1-A2-A3-A4-A5-A6-Tc where one of the moieties is in the D-configuration. A1 and A2 are each a basic polar amino acid while each of A3, A4, and A6 is a hydrophobic amino acid. A5 can be a variety of structures and appears to function to optimize the spatial relationship between the hydrophobic and the basic residues. TN is selected or modified to convey resistance against enzymatic degradation. Tc is an amino group or an amidated amino acid, preferably hydrophobic.

Affiliated with

Also associated with

Rating

Anti-inflammatory peptide analogs and treatment to inhibit... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Anti-inflammatory peptide analogs and treatment to inhibit..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-inflammatory peptide analogs and treatment to inhibit... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1522542