Anti-inflammatory preparation

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 57/03 (2006.01) A61K 31/20 (2006.01) A61K 31/202 (2006.01) A61K 35/56 (2006.01) C07C 69/587 (2006.01) C07C 233/09 (2006.01) C11C 1/02 (2006.01)

Patent

CA 2196422

An anti-inflammatory preparation comprises a purified, active fraction isolated from a lipid extract of Perna canaliculus or Mytilus edulis, or an active component thereof. The compound 5,11,14,17-eicosatetraenoic acid may be a major constituent of the active fraction. A substantially pure form of 5,11,14,17-eicosatetraenoic acid is isolated and pharmaceutically acceptable esters, amides and salts thereof identified. These compounds are also used in anti-inflammatory preparations and treatments.

La préparation anti-inflammatoire comprend une fraction active, purifiée qui a été isolée d'un extrait lipidique de Perna canaliculus ou Mytilus edulis, ou un composant actif de ceux-ci. Le composé d'acide 5,11,14,17-eicosatétraénoïque peut être un constituant principal de la fraction active. Une forme sensiblement pure de l'acide 5,11,14,17-eicosatétraénoïque est isolée et des esters, amides et sels pharmaceutiquement acceptables de cet acide ont été identifiés. Ces composés sont utilisés dans des traitements et préparations anti-inflammatoires.

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