C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/861 (2006.01) A61K 39/235 (2006.01) A61K 48/00 (2006.01) C07K 14/075 (2006.01) C12N 5/10 (2006.01) C12N 7/00 (2006.01) C12N 15/34 (2006.01) A61K 39/00 (2006.01)
Patent
CA 2358179
The present invention concerns a recombinant adenoviral vector derived from an adenovirus genome in which at least a part of the E3 region is deleted on is non functional, wherein said adenoviral vector retains E3 sequences encoding a functional 14.7K protein, a functional 14.5K protein, and/or a functional 10.4K protein. The present invention further relates to the use of a polynucleotide comprising at least one or more gene(s) of an E3 region of an adenovirus, taken individually or in combination, to protect from an inflammatory reaction in a host cell, tissue or organism. The present invention additionally concerns a viral particle, a host cell and a composition comprising said recombinant adenoviral vector or said polynucleotide, as well as their use for therapeutic or prophylactic purpose.
Ridout & Maybee Llp
Transgene S.a.
LandOfFree
Anti-inflammatory vectors does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Anti-inflammatory vectors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Anti-inflammatory vectors will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1887807